The antithyroid drugs methimazole (MMI) and propylthiouracil (PTU) are used as one option to treat patients with hyperthyroidism, especially those with Graves' disease. Thyroid Problems: Extremes Are Never Good. Patient does not provide medical advice, diagnosis or treatment. manic bipolar unable to get along with others. Twice, I got worried because my hand and arm were deep red from the tightness of the cuff. While many people understandably want to stop taking their thyroid medication immediately, the best approach is to begin the protocol and then begin to gradually wean off the thyroid medication under the supervision of a medical doctor. When your lab tests are like yours (low TSH and high Free T4) you are hyper. Your healthcare provider will check your thyroid levels and adjust your dose as needed. I am feeling ok just scared that I will be back to where I was 2 years ago, but with Gods help and my awesome doctor I hope that it will be all good. Some people have Graves alone, some have Hashi's alone and some people have both Graves and Hashi's at the same time. To me, it really is the missed mimic of several disease states, as described above in our possibly uroseptic patient. I started off with relatively normal levels but my doc found nodules. Dr.DanielleWeiss is the founder of the Center for Hormonal Health and Well-Being, a personalized, proactive, patient-centered medical practice with a unique focus on integrative endocrinology. Yet to you, something does not seem right. It is not really safe to stop it suddenly. Or, you could be experiencing over-treatment, meaning that you need a dose adjustment or a different medication. Worsening of constipation or GI issues. I said ok, not thinking anything of it, but after halving my dose for a few weeks Ive started to feel bad again. We offer this Site AS IS and without any warranties. As far as symptoms go, I have been gassy (for no reason), fatigued more than usual, depressed, short tempered,and I'm either too cold or too hot. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Talk to your doctor about these issues, as they can be the effects of your thyroid hormone levels getting back to normal. I do have Hashitoxicosis so I remember you saying that I won't respond as well to methimazole. Methods: We retrospectively studied patients with Graves' disease who were initially on MMI, in whom this drug was stopped because they had undetectable thyroid-stimulating antibodies (TSAbs) or were euthyroid after at least 24 months on MMI treatment. 2. You should not use methimazole if you are allergic to it, or: To make sure methimazole is safe for you, tell your doctor if you have: Using methimazole during pregnancy could harm the unborn baby. Severe hyperthyroidism: 60 mg orally per day. I was on 10mg daily of Tapazole, went to 7.5 in the early winter but also returned to work at same time (bad idea). Yes, Ive had doctors try to wean me off twice. There are experiences, however, that may cause you to question the benefits of your medications and not stick with your treatment plan. Good luck, hope you go into remission! rachelemacd Hypothyroidism (underactive thyroid). A list of national and international resources and hotlines to help connect you to needed health and medical services. My plan is to try to get down to 10MG per week by May..then 5mg per week by summer and then nothing after that. So I don't think there is one size fits all but I do believe you need the information from the tests your doc does as well as learning about your body and its symptoms and what works and what doesn't in order to get well. We aim to disrupt how medical providers and trainees can gain public access to high-quality, educational content while also engaging in a dialogue about best-practices in EM and medical education. It is also taken before thyroid surgery or radioactive iodine therapy. Some clinicians recommend discontinuing methimazole 2-7 days before radioactive iodine; may restart methimazole 3-7 days after radioactive iodine, then generally taper over 4-6 weeks as thyroid function normalizes and radioactive iodine becomes effective. Try our Symptom Checker Got any other symptoms? Some side effects may occur that usually do not need medical attention. In the case of our patient above, both laboratory parameters and the overall clinical picture confirm our suspicion of thyroid storm. You have a 54-year-old female who presents to the emergency department with a chief complaint of just feeling out of it. She has felt off and on for the past 12 hours and has had an occasional cough with some sputum production along with the shakes and chills. She also feels as if her heart was going at a mile a minute and because of this, she is very much out of breath. A list of national and international resources and hotlines to help connect you to needed health and medical services. Methimazole can lower blood cells that help your body fight infections and help your blood to clot. Sorry you're having these problems. Good luck!!! and he said that it could not be my thyroid because the Methimazole will be in my blood for 2-3 weeks. Was there any tapering of the dose at all? Gaitonde DY, Rowley K, Sweeney L. Hypothyroidism: An update. If a child is using this medicine, tell your doctor if the child has any changes in weight. If the hyperthyroidism returns, the antithyroid drugs are re-started. doc. I take 5 mg at night and 2.5 in the morning. Have been on it for 18 months. I would ask to do labs again. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Is There a Best Time to Take Your Thyroid Medication? She enjoys giving lectures and writing articles for both the lay public and medical audiences. Even while I was having a thyroid storm and my hr was way to high it took the doctor telling me I was going to die before I let him give me meds to slow my heart. How long were you on Methimazole before weaning off? :), The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. But he also closely monitored my levels after weaning off, bloodwork once a week for a while to make sure things stayed normal. It can also increase the risk of developing a dangerous condition known asthyroid storm, which has a high fatality rate. But the symptoms and side effects associated with thyroid disease can make it difficult to know whether you feel better overall with or without your thyroid medication. Home Treatment For Low Thyroid: What Essential Oils Are Good For Hypothyroidism? I refused to take blood pressure the whole time. ChildrenDose is based on body weight and must be determined by your doctor. I am so overwhelmed and only end up having a few days out of a month. My pcp didn't like that. Gimel is right, it only has a 6 hour half life. I have been taking the same dosages for all those years, except my dosage for Methimazole was brought down to 1 and 1/2 pills (5 mg pills) about a year ago. Just like a person with type 1 diabetes needs insulin, you need thyroid hormonefor survival. He naturally handcuffed me and searched my car in which I had marijuwana and had already told him. Press question mark to learn the rest of the keyboard shortcuts. Not all possible interactions are listed in this medication guide. Been on Tapazole for 13 months after being diagnosed with graves disease. Dr. Fereidoun Azizi. Do not give this medicine to a child without medical advice. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. But didnt feel any on the 5 mg. How long were you on Methimazole before weaning off? I'd get night sweats and have trouble sleeping. You should not shock your body that way. You pituitary is trying to tell your thyroid to produce more hormones, but the Methimazole (anti-thyroid med) is preventing your thyroid from working. Read our editorial policy. This was very irresponsible of them and I was not able to be well enough to work for a year after that. If you are hypothyroidwhether due to Hashimoto's, Graves' disease treatment, thyroid surgery, or congenital hypothyroidismfailing to take your thyroid hormone replacement medication can pose many risks to your health. What dose were you on to start with? My T's were always mid range. It works by making it harder for the body to make thyroid hormone. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. If true allergy to iodine or contraindication to iodine therapy (e.g. They were always very high. Ive had this suggested to me by multiple drs so its not just my current one. So this is a surprise to me that I migh have Graves or toxic nodules as I feel I'm bouncing back with no symptoms of hyper. Having irrational thoughts worries. I think it's common to wean off after being in normal range for 12-18 months to see if it's gone into remission, that's what my endocrinologist did the first time my graves was diagnosed. Im feeling exactly those symptoms minus the weight loss because that hasnt changed on 2.5. Recently, after a six month stint of being in the normal range, my bloodwork indicated I was hyper. 7 Tips To Manage Heavy, Painful Or Irregular Periods When You Have Hypothyroidism. Being short tempered can go along with being fatigued and/or depressed or not feeling well in general. Coming Off Percocet (Endocet) Or Oxycodone. Because I thought they might be responsible for lowering TSH. Herpes spreads by oral, vaginal and anal sex. Do Thyroid Problems Always Have To Be Treated? Found that I could not take vitamin D pills, that they had to be the gel caps. I think its common to wean off after being in normal range for 12-18 months to see if its gone into remission, thats what my endocrinologist did the first time my graves was diagnosed. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Call your doctor for medical advice about side effects. When I say all is good, my TSH level is still less than .01 but that takes longer to bounce back. If you are feeling unsure about your thyroid medication, it is a good idea to think about the reasons why and to talk about them with your doctor. I'm not in hypo yet I don't think the doctors just think that I'm going into hypo..? :-). Some of the effects of skipping or stopping your thyroid medication are obvious, while others are so subtle they can go undiagnosed for years. Natural Solutions For Graves' Disease & Hashimoto's Thyroiditis. Paying for medications can be stressful. Levels of hormone can swing up quickly. One thing my Endo and I agree on is that he will not stop a patient's medication entirely unless their antibody levels are within the normal range even if all their thyroid labs are normal. no one will listen. Said it was controversial. unusual bleeding or bruising. The anxiety and the eye problem could be symptoms of Hyperthyroid, or it might be unrelated. Solomon B, Wartofsky L, Burman K. Adjunctive cholestyramine therapy for thyrotoxicosis. The maintenance dose is 5 to 15 mg per day. When starting medication, your appetite may change, you may be feeling tired, or you could have a change in your bowel movements. It should always be tapered incredibly gradually, there's always a small rebound period for me no matter how small I chop it with my pill cutter. And I am still could thins be a side affect of relapse or not taking my meds? It got to the point where I could barely eat. We want the forums to be a useful resource for our users but it is important to remember that the forums are When I go back in May, he will probably wean down to 25 mg a week. Okay I didn't know you had completely stopped the Methimazole, but I think you misread what I wrote. It is also used before thyroid surgery or radioactive iodine treatment. Shaky? Hello I'm glad I found this. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. ALiEM is your digital connection to the cooperative world of EM. By using this Site you agree to the following, By using this Site you agree to the following, The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life. You should go off it slowly. Not taking your hypothyroid or hyperthyroid medication can cause undesirable, dangerous, and even life-threatening conditions, ranging from fatigue and changes in blood pressure to death. Could the anxiety be stemming from you actually still needing the methimazole? Usual Pediatric Dose for Hyperthyroidism: Initial dose: 0.4 mg/kg orally per dayMaintenance dose: 0.2 mg/kg orally per day (approximately half the initial dose) Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals. She has a past medical history of hypertension and she has been compliant with her medications. Now I have to start all over again. It was the Acetyl-L-Carnitine that really worked for me and from other boards seems to work for Graves patients. A dosage change can start to be felt for me in 3 days and reaches fullness in about a week, but if it is too big a dosage change the symptoms can last for week (s) afterward till my body adjusts. Avoid being near people who are sick or have infections. That is a real challenge but I know one lady with both Graves and Hashi's who got treated by a Naturopath who was able to keep her thyroid levels normal with just the natural methods. I'd love to be able to start these again once I'm diagnosed and under the care of a naturopath. Am Fam Physician. I'm very upset because I figure he's the doctor and shouldn't have left that choice up to me. His goal is to wean me off very slowly. Make sure you get tested monthly while getting weaned off. 6 years ago, Stop using methimazole and call your doctor right away if you have signs of infection such as: sudden weakness or ill feeling, fever, chills, sore throat, cold or flu symptoms; painful mouth sores, pain when swallowing, red or swollen gums; or. Herpes spreads by oral, vaginal and anal sex. i am afraid of going hyper again, they told me to wean off i tried just quiting then had major panic attack and went back on the medication I feel off balance and am having anxiety my eyes hurt and I dont know if its me making myself feel that way or it is my thyroid, I will get my labs next week to see if i am still normal i only had post partum hyprethyroid, and i probably really nevre needed the medication because my tsh was low but had normal t3 t4. Egton Medical Information Systems Limited. Initial dose: Mild hyperthyroidism: 15 mg orally per dayModerately severe hyperthyroidism: 30 to 40 mg orally per daySevere hyperthyroidism: 60 mg orally per day Maintenance dose:5 to 15 mg orally per day Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervalsUses: -For the treatment of Graves' disease with hyperthyroidism or toxic multinodular goiter in whom surgery or radioactive iodine therapy is not an appropriate treatment option.-To ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy. 0.84 t4 sounds pretty low so maybe that was part of the decision? This exact thing happened to me and then my endo put me back on it and my body couldnt tolerate it I was passing out and my symptoms were so much worse,. Please get back to me.. even my hair started falling out and to me to be a woman and have your hair fall out is the worst thing in the world. Endocrinologic emergencies often fall at the wayside and are not generally considered as a possible diagnosis up front in patients in the emergency department who meet the criteria for systemic inflammatory response syndrome (SIRS). I found out the hard way. It is FREE! While you may experience some symptoms of overactive thyroid more than others, and you may even consider some of them beneficial, it is important to be aware of the strain this condition is putting on your heart, bones, and overall health. How Are Thyroid Disorders Linked To An Increased Risk Of Developing Osteoporosis? To become an empowered patient, you need to obtain a copy of any medical documentation done on you, either lab tests or reports from other physicians and keep your own file so you can see your progresss. I was on 5 mg daily and now my dr halved it to 2.5 daily. Tenner AG, Halvorson KM. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Is there some other underlying issue that is taking place? I was taken to jail where I was geld for two weeks without my medicine and let me tell you I got sick with peripheral edema, vasculitis. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Thyroid level saga continuespart 20. T3 total: 332; FT3 11.1; FT4 387, TSH <.005. Endocrine causes of dangerous Fever. https://patient.info/forums/discuss/stopping-methimazole-543742. I'm afraid the L Carnitine I'll make me have more symptoms. Same as sudden weather changes, we get headaches etc. Homeopathic remedy for overactive thyroid, Graves' Disease: Symptoms, Treatment And Complications, Graves' Disease: Symptoms, Diagnosis And Treatment, Holistic Approach to Thyroid Related Problems: Naturopathic Medicine for Thyroid Disease. Why Your Thyroid Hormone Levels May Be Fluctuating, Medications Used to Treat Thyroid Disease, Hyperthyroidism vs. Hypothyroidism: Differences and Symptoms, Thyroid Disease Facts and Statistics: What You Need to Know, Guide to Dietary Supplements and Thyroid Disease. 0.84 t4 sounds pretty low so maybe that was part of the decision? Mary Shomon is a writer and hormonal health and thyroid advocate. They are still really active so she changed her mind and I am staying on the medication. You may need a different medication or a dose adjustment, but you should never quit your medication without your doctor's approval. So hopefully youre getting bloodwork again soon to make sure things are ok? How should this medicine be used? Burch H, Wartofsky L. Life-threatening thyrotoxicosis. Are you losing weight? I have hyper numbers - very low TSH and high/normal T4 and I have the same kind of symptoms you have: freezing cold and sometimes achy legs. Sulfamethoxazole-Trimethoprim for Skin and Soft Tissue Infections: 1 or 2 Tablets BID? Methimazole is used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. I feel like lying on a hot beach would cure me for life lol but I live on a mountain! I occasionally would ask my husband what the readings were. They do better controlling their thyroid hormones using Regular L-Carnitine. Her overall presentation does not seem to add up in being secondary to urosepsis. Hyperthyroidism can cause unwanted symptoms like anxiety and excessive sweating. My tsh leve as of yesterday dropped down to 3.65 so I'm in range again ref range is 0.34-4.82. Debilitating fatigue; tiredness; pressure in head - related, Diagnosed with Graves' disease - my symptoms are high pulse, loose stools and very tired, Graves Disease - Hyperthyroid does anyone have the same symptoms. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You will be able to stop your methimazole or PTU immediately. I am a 52 year old female and I had been on 15MG Methimazole for the over 2 months and my Endo lower the dosage to 10MG (took the And I vote you find another endo even if you do even out - you want someone who knows their stuff to monitor you in case you relapse in the future. HI, I was diagnosed with Graves Disease last fall (2016). A previous ALiEM blog post further discusses some of the nuances associated with the diagnosis of thyroid storm. Emerg Med ClinNorth Am. I told my endo. DID YOU NOTICE ANXIETY OR RAPID HEARTBEAT OR COULD I BE ANXIOUS ABOUT GETTING OFF THE MEDICATION. Press J to jump to the feed. 2 days on, one day off and this past week my endocrinologist gave me the choice of either going right off Tapazole or going off it slowly. Treatment of hyperthyroidism with a combination of methimazole and cholestyramine. It does not stay in the body for 2-3 weeks, this is just not true. Herpes sores blister, then burst, scab and heal. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Most of us feel best with Free T4 at about the mid range point and Free T3 in the upper half to upper third of the range. Methimazole can pass into breast milk and may harm a nursing baby. I never was given clarity about what "the damage" entailed though:(. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. She is the author of "The Thyroid Diet Revolution. Hair loss. Im going to ask to go back to my old dose because my numbers were exactly in the middle at 2.13 but now theyre probably a mess. A Community for those living with and dealing with Graves' Disease. If the patient is given PTU during treatment of thyroid storm, this should be switched to methimazole at the time of discharge unless methimazole is contraindicated. Anthing would be helpful. Also you will have more definite information when you post on sites like this and we can respond better by knowing this information rather than "my levels are going into the hypo range" we will have your actual levels which makes it better for us to respond. Call your doctor at once if you have: liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). amiodarone-induced thyrotoxicosis): Consider administration of lithium carbonate 300 mg PO or NG q6h, Maintain lithium level within range of 0.8 to 1.2 mEq/L, Enhanced - and -adrenergic stimulation in the setting of thyroid storm leads to clinical manifestations, Inhibits peripheral conversion of T4 to T3 (3ndB), Effect not demonstrated considerably with other -antagonists, Blocks non-selective -adrenergic receptors to allow for effective treatment of systemic effects, such as tremor, tachycardia, agitation, fever, diaphoresis, psychosis (2nd B), Proper dosing of propranolol is essential because ofdose-dependent effects on inhibition of peripheral conversion of thyroid hormone (> 160 mg/day), and rapid metabolism of the agent in the setting of thyroid storm, Alternative route of propranolol: IV formulation (determine availability at your institution), Test dose: 0.5 to 1 mg as slow IV push administered over 10 minutes, Subsequent doses: 1 to 3 mg IV over 10 to 15 minutes every few hours to desired effect with monitoring of cardiac rhythm, Contraindications to beta blockade: guanethidine or reserpine with close monitoring for hypotension, Depression of the hypothalamic-pituitary axis commonly occurs in the setting of thyroid storm, Additional benefit: inhibition of peripheral conversion of T4 to T3 (3rd B), Can be used to interrupt enterohepatic recirculation of thyroid hormone, leading to decreased circulating levels of thyroid hormone, Dissipation of heat with various cooling modalities for hyperthermia control, Benzodiazepines for control of agitation and to minimize sympathetic outflow. STIs are the most common cause of genital sores. Serious and sometimes fatal infections may occur during treatment with methimazole. I have been having anxiety attacks and I have only been off it a week. All rights reserved. I was diagnosed with Autoimmune Hyperthyroidism in Dec., 2006. There are 3 kinds of L Carnitine suppslements what kind did you take to help? This article covers the possible risks of not taking your hypothyroidism or hyperthyroidism medication. I also wanted to know my Carnitine levels before I started taking it so I asked my doc to give me a requisition to get it tested and found I was deficient. HyperT77 My Endocrinologist has started weaning me off of Methimazole. I want to know if I should see another doctor. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. You should not breast-feed while using methimazole. Now I am in none. I have my test results and I am taking 15MG Methimazole a day since 5/25 and the Endo told me to continue taking the same dosage Me again. RMMB, how much methimazole were you on before you stopped cold turkey? My blood pressure was constantly high until I was off of medications. I have very receintly been taken off Methimazole cold turkey atfter 6 years. When I was in the ER, they hooked me up to the BP cuff, and it stayed there, turning off and on the entire time. When did you start going off it? Diagnosis of thyroid storm can be somewhat of a challenge because of this, but a scoring system developed by Burch and Wartofsky 1 can assist in determining the likelihood of thyroid storm in patients based on presenting signs and symptoms. Dizziness. I feel fine. It is generally well tolerated and has few side effects, but it does require close monitoring because of a low rate of some severe side effects, such as low blood counts. Use of the forums is subject to our Terms of Use I had to do the same for 2 weeks and had no withdrawal symptoms and I was on 30mg at the time. STIs are the most common cause of genital sores. This . All of this has been a real struggle for me since I have a huge phobia of taking meds. Slowly weaning off or tapering to the right dose is the best method. I read somewhere that ALA can work on TSH. a beta blocker--atenolol, carvedilol, labetalol, metoprolol, nadolol, propranolol, sotalol, and others. appropriate medical assistance immediately. My Endocrinologist has started weaning me off of Methimazole. Skip the missed dose if it is almost time for your next scheduled dose. The problem can be changing your diet, as you don't know how the thyroid will react to this. 19 users are following. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Methimazole is an excellent medication for Grave's disease and other forms of hyperthyroidism which works by interfering with the production of the thyroid hormones. Herpes sores blister, then burst, scab and heal. Best, Rachel. as being in breach of those terms. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. As soon as they see that youre going hyper again, they should put you back on your regular dose. first cutting the 5mg tablet in half then in 1/4's. I got diagnosed with graves approx 1 year ago I responded good to tapazole however I was sick with a cold and forgot to take my meds for like a week? Previous: "Why Wasn't I Taught This Stuff In Medical School?" Anthing would be helpful. We went to the ER. What many people don't realize is that there are quite a few symptoms that can apply to either/both hyper and hypo. Slept all day, terrible itching skin especially at night while trying to sleep. I havent tried to wean off before. Hashimoto patients do better on the Regular L-Carnitine. We recommend using methimazole (MMI; 0.25 to 1.0 mg/kg per day). I don't believe our bodies respond well to abrupt changes. Nabil N, Miner D, Amatruda J. Methimazole: an alternative route of administration. We offer this Site AS IS and without any warranties. However, thyroid disease is complicated, and you can develop new symptoms when you begin your treatment, either due to the wrong medication dose or the way that your body responds to the medication. I got pulled over for speeding on Christmas eve last year. Registered in England and Wales. My methimazole was 5 mg once a day. ALiEM AIR Series | Orthopedics Lower Extremity Module. Her vital signs are blood pressure of 184/106 mmHg, heart rate of 130 beats per minute, respiratory rate of 22 breaths per minute, and temperature of 102.7F. It can take a few days to a few weeks for you to even start noticing a difference in how you feel. Endometriosis And Thyroid disease: Is There Really A Connection? Hair loss. You will learn what these results mean very quickly and you can always learn more about them online. I've read of people getting off Methimazole all at once and doing okay, although many do have "withdrawal" symptoms (symptoms of being hyper) as their body purges the medication. Get your TBII or TRAb antibodies tested for Graves, anti-TPO and TGAb for hashimoto's. not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in Metroprolol is a beta blocker that slows the heart rate.
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